Immunological Sciences

SEPT7 Rabbit Monoclonal Antibody

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Catalog Number:MABN86589
Conjugate:Unconjugated
Size:100μL
Concentration:1mg/ml
Host:Rabbit
Isotype:IgG
Clone:Monoclonal
Immunogen:Recombinant protein of human SEPT7
Reactivity:Human,Mouse,Rat
Applications:WB 1:1000-1:5000,ICC/IF 1:50-1:100
Molecular Weight:Calculated MW:51 kDa; Observed MW:51 kDa
Purification:Affinity Purification
Form:Liquid
Synonyms:CDC3; CDC10; SEPT7A; NBLA02942

Applications

WB 1:1000-1:5000,ICC/IF 1:50-1:100

Immunogen

Recombinant protein of human SEPT7

Target Background

This gene encodes a protein that is highly similar to the CDC10 protein of Saccharomyces cerevisiae. The protein also shares similarity with Diff 6 of Drosophila and with H5 of mouse. Each of these similar proteins, including the yeast CDC10, contains a GTP-binding motif. The yeast CDC10 protein is a structural component of the 10 nm filament which lies inside the cytoplasmic membrane and is essential for cytokinesis. This human protein functions in gliomagenesis and in the suppression of glioma cell growth, and it is required for the association of centromere-associated protein E with the kinetochore. Alternative splicing results in multiple transcript variants. Several related pseudogenes have been identified on chromosomes 5, 7, 9, 10, 11, 14, 17 and 19. [provided by RefSeq, Jul 2011]

Synonyms:CDC3; CDC10; SEPT7A; NBLA02942

Storage

Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.

Buffer

Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

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