Septin 7 Rabbit Monoclonal Antibody

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Catalog Number:MABN02587
Conjugate:Unconjugated
Size:100μL
Concentration:1mg/ml
Host:Rabbit
Isotype:IgG
Clone:Monoclonal
Immunogen:Recombinant protein of human SEPT7
Reactivity:Human,Mouse,Rat
Applications:WB 1:500-1:1000,ICC/IF 1:50-1:200
Molecular Weight:Calculated MW: 51 kDa; Observed MW: 51 kDa
Purification:Affinity Purification
Form:Liquid
Synonyms:septin 7; CDC3; CDC10; SEPT7; SEPT7A; NBLA02942

Applications

WB 1:500-1:1000,ICC/IF 1:50-1:200

Immunogen

Recombinant protein of human SEPT7

Target Background

Filament-forming cytoskeletal GTPase. Required for normal organization of the actin cytoskeleton. Required for normal progress through mitosis. Involved in cytokinesis. Required for normal association of CENPE with the kinetochore. Plays a role in ciliogenesis and collective cell movements. Forms a filamentous structure with SEPT12, SEPT6, SEPT2 and probably SEPT4 at the sperm annulus which is required for the structural integrity and motility of the sperm tail during postmeiotic differentiation (PubMed:25588830).

Synonyms:septin 7; CDC3; CDC10; SEPT7; SEPT7A; NBLA02942

Storage

Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.

Buffer

50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA

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