Immunological Sciences

SERPINA1 (2F7) Rabbit Monoclonal Antibody

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Catalog Number:MABN17765
Conjugate:Unconjugated
Size:100μL
Concentration:1mg/ml
Host:Rabbit
Isotype:IgG
Clone:Monoclonal
Immunogen:A synthetic peptide of human alpha 1 Antitrypsin
Reactivity:Human
Applications:WB 1:1000-1:5000,IP 1:10-1:100
Molecular Weight:47kDa
Purification:Affinity purification
Form:Liquid
Synonyms:Serpin A1; Short peptide from AAT; SPAAT; AAT;

Applications

WB 1:1000-1:5000,IP 1:10-1:100

Immunogen

A synthetic peptide of human alpha 1 Antitrypsin

Target Background

SERPINA1 is secreted and is a serine protease inhibitor which its targets include elastase, plasmin, collagenase, thrombin, leucocytic proteases, trypsin, chymotrypsin, and plasminogen activator. Inhibitor of serine proteases. Its primary target is elastase, but it also has a moderate affinity for plasmin and thrombin. Inhibitor of serine proteases. Its primary target is elastase, but it also has a moderate affinity for plasmin and thrombin. Irreversibly inhibits trypsin, chymotrypsin and plasminogen activator. The aberrant form inhibits insulin-induced NO synthesis in platelets, decreases coagulation time and has proteolytic activity against insulin and plasmin.

Synonyms:Serpin A1; Short peptide from AAT; SPAAT; AAT;

Storage

Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.

Buffer

Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% New type preservative N and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.

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