SIRT1 Rabbit Monoclonal Antibody

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Catalog Number:MABN21606
Conjugate:Unconjugated
Size:100μL
Concentration:1mg/ml
Host:Rabbit
Isotype:IgG,Kappa
Clone:Monoclonal
Immunogen:A synthetic peptide corresponding to target protein
Reactivity:Human,Rat,
Applications:WB 1:1000-1:5000,IHC 1:100-1:200,ICC/IF 1:200-1:1000,ELISA 1:5000-1:20000,IP 1:50-1:200
Molecular Weight:CalcuLated MW:81kD;Observed MW:130kD
Purification:Protein A
Form:Liquid
Synonyms:SIRT1;SIR2L1;NAD-dependent protein deacetylase sirtuin-1;hSIRT1;ReguLatory protein SIR2 homolog 1;SIR2-like protein 1;hSIR2

Applications

WB 1:1000-1:5000,IHC 1:100-1:200,ICC/IF 1:200-1:1000,ELISA 1:5000-1:20000,IP 1:50-1:200

Immunogen

A synthetic peptide corresponding to target protein

Target Background

Cell localization:Nuclear.This gene encodes a member of the sirtuin family of proteins, homologs to the yeast Sir2 protein. Members of the sirtuin family are characterized by a sirtuin core domain and grouped into four classes. The functions of human sirtuins have not yet been determined; however, yeast sirtuin proteins are known to regulate epigenetic gene silencing and suppress recombination of rDNA. Studies suggest that the human sirtuins may function as intracellular regulatory proteins with mono-ADP-ribosyltransferase activity. The protein encoded by this gene is included in class I of the sirtuin family. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2008],

Synonyms:SIRT1;SIR2L1;NAD-dependent protein deacetylase sirtuin-1;hSIRT1;ReguLatory protein SIR2 homolog 1;SIR2-like protein 1;hSIR2

Storage

Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.

Buffer

PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA

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