SIRT1 Rabbit Monoclonal Antibody

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Catalog Number:MABN86728
Conjugate:Unconjugated
Size:100μL
Concentration:1mg/ml
Host:Rabbit
Isotype:IgG
Clone:Monoclonal
Immunogen:A synthetic peptide of human SIRT1
Reactivity:Human
Applications:WB 1:2000-1:20000,IHC 1:100-1:200,ICC/IF 1:100-1:200,FC 1:100-1:200,IP 1:20-1:50
Molecular Weight:Calculated MW:82 kDa; Observed MW:120 kDa
Purification:Affinity Purification
Form:Liquid
Synonyms:SIR2; SIR2L1; SIR2alpha

Applications

WB 1:2000-1:20000,IHC 1:100-1:200,ICC/IF 1:100-1:200,FC 1:100-1:200,IP 1:20-1:50

Immunogen

A synthetic peptide of human SIRT1

Target Background

This gene encodes a member of the sirtuin family of proteins, homologs to the yeast Sir2 protein. Members of the sirtuin family are characterized by a sirtuin core domain and grouped into four classes. The functions of human sirtuins have not yet been determined; however, yeast sirtuin proteins are known to regulate epigenetic gene silencing and suppress recombination of rDNA. Studies suggest that the human sirtuins may function as intracellular regulatory proteins with mono-ADP-ribosyltransferase activity. The protein encoded by this gene is included in class I of the sirtuin family. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2008]

Synonyms:SIR2; SIR2L1; SIR2alpha

Storage

Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.

Buffer

Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

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