Immunological Sciences

SIRT3 Rabbit Monoclonal Antibody

No images available

Catalog Number:MABN21475
Conjugate:Unconjugated
Size:100μL
Concentration:1mg/ml
Host:Rabbit
Isotype:IgG,Kappa
Clone:Monoclonal
Immunogen:A synthetic peptide of human SIRT3
Reactivity:Human,Mouse,Rat,
Applications:WB 1:1000-1:5000,IHC 1:200-1:1000,ICC/IF 1:200-1:1000,ELISA 1:5000-1:20000,IP 1:50-1:200
Molecular Weight:CalcuLated MW:44kD;Observed MW:28kD
Purification:Protein A
Form:Liquid
Synonyms:SIRT3;SIR2L3;NAD-dependent protein deacetylase sirtuin-3;mitochondrial;hSIRT3;ReguLatory protein SIR2 homolog 3;SIR2-like protein 3

Applications

WB 1:1000-1:5000,IHC 1:200-1:1000,ICC/IF 1:200-1:1000,ELISA 1:5000-1:20000,IP 1:50-1:200

Immunogen

A synthetic peptide of human SIRT3

Target Background

Cell localization:Mitochondrion matrix.This gene encodes a member of the sirtuin family of proteins, homologs to the yeast Sir2 protein. Members of the sirtuin family are characterized by a sirtuin core domain and grouped into four classes. The functions of human sirtuins have not yet been determined; however, yeast sirtuin proteins are known to regulate epigenetic gene silencing and suppress recombination of rDNA. Studies suggest that the human sirtuins may function as intracellular regulatory proteins with mono-ADP-ribosyltransferase activity. The protein encoded by this gene is included in class I of the sirtuin family. Two alternatively spliced transcript variants that encode different proteins have been described for this gene. [provided by RefSeq, Jul 2008],

Synonyms:SIRT3;SIR2L3;NAD-dependent protein deacetylase sirtuin-3;mitochondrial;hSIRT3;ReguLatory protein SIR2 homolog 3;SIR2-like protein 3

Storage

Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.

Buffer

PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA

No documents available.