SIRT6 Rabbit Monoclonal Antibody

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Catalog Number:MABN86993
Conjugate:Unconjugated
Size:100μL
Concentration:1mg/ml
Host:Rabbit
Isotype:IgG
Clone:Monoclonal
Immunogen:A synthetic peptide of human SIRT6
Reactivity:Human
Applications:WB 1:1000-1:5000
Molecular Weight:Calculated MW:39 kDa; Observed MW:39 kDa
Purification:Affinity Purification
Form:Liquid
Synonyms:SIR2L6

Applications

WB 1:1000-1:5000

Immunogen

A synthetic peptide of human SIRT6

Target Background

This gene encodes a member of the sirtuin family of NAD-dependent enzymes that are implicated in cellular stress resistance, genomic stability, aging and energy homeostasis. The encoded protein is localized to the nucleus, exhibits ADP-ribosyl transferase and histone deacetylase activities, and plays a role in DNA repair, maintenance of telomeric chromatin, inflammation, lipid and glucose metabolism. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Mar 2016]

Synonyms:SIR2L6

Storage

Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.

Buffer

Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

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