SLAMF6 Rabbit Monoclonal Antibody

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Catalog Number:MABN87564
Conjugate:Unconjugated
Size:100μL
Concentration:1mg/ml
Host:Rabbit
Isotype:IgG
Clone:Monoclonal
Immunogen:Recombinant protein of human SLAMF6
Reactivity:Human
Applications:WB 1:500-1:2000,ICC/IF 1:500-1:1000,FC 1:200-1:500,IP 1:20-1:50
Molecular Weight:Calculated MW:37 kDa; Observed MW:60 kDa
Purification:Affinity Purification
Form:Liquid
Synonyms:KALI; NTBA; CD352; KALIb; Ly108; NTB-A; SF2000

Applications

WB 1:500-1:2000,ICC/IF 1:500-1:1000,FC 1:200-1:500,IP 1:20-1:50

Immunogen

Recombinant protein of human SLAMF6

Target Background

The protein encoded by this gene is a type I transmembrane protein, belonging to the CD2 subfamily of the immunoglobulin superfamily. This encoded protein is expressed on Natural killer (NK), T, and B lymphocytes. It undergoes tyrosine phosphorylation and associates with the Src homology 2 domain-containing protein (SH2D1A) as well as with SH2 domain-containing phosphatases (SHPs). It functions as a coreceptor in the process of NK cell activation. It can also mediate inhibitory signals in NK cells from X-linked lymphoproliferative patients. Alternative splicing results in multiple transcript variants encoding distinct isoforms.[provided by RefSeq, May 2010]

Synonyms:KALI; NTBA; CD352; KALIb; Ly108; NTB-A; SF2000

Storage

Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.

Buffer

Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

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