Immunological Sciences

SLC43A1 Rabbit Polyclonal Antibody

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Catalog Number:ABN17958
Conjugate:Unconjugated
Size:100μL
Concentration:1mg/ml
Host:Rabbit
Isotype:IgG
Clone:Polyclonal
Immunogen:The antiserum was produced against synthesized peptide derived from human LAT3. AA range:231-280
Reactivity:Human,Rat,Mouse
Applications:WB 1:500-1:2000,IHC 1:50-1:300,ELISA 1:2000-1:20000
Molecular Weight:61kDa
Purification:Affinity purification
Form:Liquid
Synonyms:SLC43A1; LAT3; PB39; POV1; Large neutral amino acids transporter small subunit 3; L-type amino acid transporter 3; Prostate cancer overexpressed gene 1 protein; Solute carrier family 43 member 1

Applications

WB 1:500-1:2000,IHC 1:50-1:300,ELISA 1:2000-1:20000

Immunogen

The antiserum was produced against synthesized peptide derived from human LAT3. AA range:231-280

Target Background

SLC43A1 belongs to the system L family of plasma membrane carrier proteins that transports large neutral amino acids (Babu et al., 2003 [PubMed 12930836]).[supplied by OMIM, Mar 2008],function:Sodium-independent, high affinity transport of large neutral amino acids. Has narrower substrate selectivity compared to SLC7A5 and SLC7A8 and mainly transports branched-chain amino acids and phenylalanine. Plays a role in the development of human prostate cancer, from prostatic intraepithelial neoplasia to invasive prostate cancer.,miscellaneous:Up-regulated in early prostate cancer development with highest expression level in seminomas of testicular germ cell tumors.,similarity:Belongs to the SLC43A transporter (TC 2.A.1.44) family.,tissue specificity:In adults, found in all tissues examined with highest expression in pancreas. In fetus, highest expression in liver and lower levels in kidney, and lung. High levels found in prostate cancer cells.,

Synonyms:SLC43A1; LAT3; PB39; POV1; Large neutral amino acids transporter small subunit 3; L-type amino acid transporter 3; Prostate cancer overexpressed gene 1 protein; Solute carrier family 43 member 1

Storage

Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.

Buffer

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.

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