Immunological Sciences

SLC6A8 Rabbit Polyclonal Antibody

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Catalog Number:ABN17963
Conjugate:Unconjugated
Size:100μL
Concentration:1mg/ml
Host:Rabbit
Isotype:IgG
Clone:Polyclonal
Immunogen:The antiserum was produced against synthesized peptide derived from human SLC6A8. AA range:581-630
Reactivity:Human,Mouse,Rat
Applications:WB 1:500-1:2000,IHC 1:50-1:300
Molecular Weight:70kDa
Purification:Affinity purification
Form:Liquid
Synonyms:SLC6A8; Sodium- and chloride-dependent creatine transporter 1; CT1; Creatine transporter 1; Solute carrier family 6 member 8

Applications

WB 1:500-1:2000,IHC 1:50-1:300

Immunogen

The antiserum was produced against synthesized peptide derived from human SLC6A8. AA range:581-630

Target Background

The protein encoded by this gene is a plasma membrane protein whose function is to transport creatine into and out of cells. Defects in this gene can result in X-linked creatine deficiency syndrome. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2008],disease:Defects in SLC6A8 are the cause of X-linked creatine deficiency syndrome [MIM:300352]. X-linked creatine deficiency syndrome causes developmental delay, hypotonia, mental retardation, seizures, short stature and midface hypoplasia.,function:Required for the uptake of creatine in muscles and brain.,similarity:Belongs to the sodium:neurotransmitter symporter (SNF) family.,tissue specificity:Predominantly expressed in skeletal muscle and kidney. Also found in brain, heart, colon, testis and prostate.,

Synonyms:SLC6A8; Sodium- and chloride-dependent creatine transporter 1; CT1; Creatine transporter 1; Solute carrier family 6 member 8

Storage

Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.

Buffer

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.

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