SMC3 Rabbit Monoclonal Antibody

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Catalog Number:MABN83913
Conjugate:Unconjugated
Size:100μL
Concentration:1mg/ml
Host:Rabbit
Isotype:IgG
Clone:Monoclonal
Immunogen:A synthesized peptide derived from human SMC3
Reactivity:Human,Mouse,Rat
Applications:WB 1:1000-1:2000,IHC 1:100-1:200,ICC/IF 1:50-1:200,ICC 1:50-1:200,FC 1:20-1:100
Molecular Weight:Calculated MW: 142 kDa ; Observed MW: 141 kDa
Purification:Affinity Purification
Form:Liquid
Synonyms:SMC protein 3; Bamacan; SMC3; BAM; BMH; CSPG6; SMC3L1;;SMC3

Applications

WB 1:1000-1:2000,IHC 1:100-1:200,ICC/IF 1:50-1:200,ICC 1:50-1:200,FC 1:20-1:100

Immunogen

A synthesized peptide derived from human SMC3

Target Background

Central component of cohesin, a complex required for chromosome cohesion during the cell cycle. The cohesin complex may form a large proteinaceous ring within which sister chromatids can be trapped. At anaphase, the complex is cleaved and dissociates from chromatin, allowing sister chromatids to segregate. Cohesion is coupled to DNA replication and is involved in DNA repair. The cohesin complex also plays an important role in spindle pole assembly during mitosis and in chromosomes movement.

Synonyms:SMC protein 3; Bamacan; SMC3; BAM; BMH; CSPG6; SMC3L1;;SMC3

Storage

Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.

Buffer

Purified antibody in PBS with 0.05% sodium azide,0.05% BSA and 50% glycerol.

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