SOD1 Rabbit Polyclonal Antibody

Western blot analysis of 1) Hela, 2) MCF7, 3) Mouse Brain Tissue, 4) Rat Brain Tissue using SOD1 Polyclonal Antibody. Secondary antibody was diluted at 1:20000

Western blot analysis of 1) Hela, 2) MCF7, 3) Mouse Brain Tissue, 4) Rat Brain Tissue using SOD1 Polyclonal Antibody. Secondary antibody was diluted at 1:20000

Catalog Number:AB-80162
Conjugate:unconjugated
Size:100 ug
Concentration:1 mg/ml
Host:Rabbit
Isotype:IgG
Clone:Polyclonal
Immunogen:Synthesized peptide derived from the Internal region of human SOD-1.
Reactivity:Human;Mouse;Rat
Applications:Western Blot: 1/500 - 1/2000.IHC-p:1:50-300. Not yet tested in other applications.
Molecular Weight:18kD
Purification:The antibody was affinity-purified fromrabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Form:liquid
Synonyms:SOD1; Superoxide dismutase [Cu-Zn]; Superoxide dismutase 1; hSod1

The protein encoded by this gene binds copper and zinc ions and is one of two isozymes responsible for destroying free superoxide radicals in the body. The encoded isozyme is a soluble cytoplasmic protein, acting as a homodimer to convert naturally-occuring but harmful superoxide radicals to molecular oxygen and hydrogen peroxide. The other isozyme is a mitochondrial protein. Mutations in this gene have been implicated as causes of familial amyotrophic lateral sclerosis. Rare transcript variants have been reported for this gene.

Applications

Western Blot: 1/500 - 1/2000.IHC-p:1:50-300. Not yet tested in other applications.

Immunogen

Synthesized peptide derived from the Internal region of human SOD-1.

Target Background

The protein encoded by this gene binds copper and zinc ions and is one of two isozymes responsible for destroying free superoxide radicals in the body. The encoded isozyme is a soluble cytoplasmic protein, acting as a homodimer to convert naturally-occuring but harmful superoxide radicals to molecular oxygen and hydrogen peroxide. The other isozyme is a mitochondrial protein. Mutations in this gene have been implicated as causes of familial amyotrophic lateral sclerosis. Rare transcript variants have been reported for this gene.

Synonyms:SOD1; Superoxide dismutase [Cu-Zn]; Superoxide dismutase 1; hSod1

Storage

Store at -20°C. Avoid repeated freeze-thawcycles.

Buffer

Liquid in PBS containing 50% glycerol, 0.5%BSAand0.02% sodium azide

Western blot analysis of 1) Hela, 2) MCF7, 3) Mouse Brain Tissue, 4) Rat Brain Tissue using SOD1 Polyclonal Antibody. Secondary antibody was diluted at 1:20000

Immunohistochemical analysis of paraffin-embedded Mouse Kidney Tissue using SOD1 Polyclonal Antibody.

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