Immunological Sciences

SOD2 (12J6) Rabbit Monoclonal Antibody

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Catalog Number:MABN18098
Conjugate:Unconjugated
Size:100μL
Concentration:1mg/ml
Host:Rabbit
Isotype:IgG
Clone:Monoclonal
Immunogen:A synthetic peptide of human SOD2
Reactivity:Human,Mouse,Rat
Applications:WB 1:500-1:2000,IHC 1:100-1:200,IF-P 1:100-1:200
Molecular Weight:25kDa
Purification:Affinity purification
Form:Liquid
Synonyms:SOD2; IPOB; MNSOD; MVCD6;

Applications

WB 1:500-1:2000,IHC 1:100-1:200,IF-P 1:100-1:200

Immunogen

A synthetic peptide of human SOD2

Target Background

SOD-2 is a homotetrameric manganese enzyme (also known as MnSOD) that functions in the mitochondrion. ROS are implicated in a wide range of degenerative processes, including Alzheimer’s disease, Parkinson’s disease and ischemic heart disease. Homozygous mutant mice, which lack SOD-2, exhibit dilated cardiomyopathy, accumulation of lipid in liver and skeletal muscle, metabolic acidosis, oxidative DNA damage and respiratory chain deficiencies in heart and skeletal muscle. Destroys superoxide anion radicals which are normally produced within the cells and which are toxic to biological systems.

Synonyms:SOD2; IPOB; MNSOD; MVCD6;

Storage

Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.

Buffer

Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% New type preservative N and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.

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