SOD2 (4C4) Mouse Monoclonal Antibody

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Catalog Number:MABN03562
Conjugate:Unconjugated
Size:100μL
Concentration:1mg/ml
Host:Mouse
Isotype:IgG2b
Clone:Monoclonal
Immunogen:A synthetic peptide of human SOD2
Reactivity:Human
Applications:WB 1:500-1:1000
Molecular Weight:Calculated MW: 25 kDa; Observed MW: 22 kDa
Purification:Affinity Purification
Form:Liquid
Synonyms:IPOB; IPO-B; MNSOD; MVCD6; Mn-SOD; SOD2

Applications

WB 1:500-1:1000

Immunogen

A synthetic peptide of human SOD2

Target Background

SOD-2 is a homotetrameric manganese enzyme (also known as MnSOD) that functions in the mitochondrion. ROS are implicated in a wide range of degenerative processes, including Alzheimer’s disease, Parkinson’s disease and ischemic heart disease. Homozygous mutant mice, which lack SOD-2, exhibit dilated cardiomyopathy, accumulation of lipid in liver and skeletal muscle, metabolic acidosis, oxidative DNA damage and respiratory chain deficiencies in heart and skeletal muscle.

Synonyms:IPOB; IPO-B; MNSOD; MVCD6; Mn-SOD; SOD2

Storage

Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.

Buffer

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3.

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