SOX11 (12Z19) Rabbit Monoclonal Antibody

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Catalog Number:MABN18127
Conjugate:Unconjugated
Size:100μL
Concentration:1mg/ml
Host:Rabbit
Isotype:IgG
Clone:Monoclonal
Immunogen:A synthetic peptide of human SOX11
Reactivity:Human
Applications:WB 1:500-1:2000,IHC 1:100-1:200,IF-P 1:100-1:200
Molecular Weight:47kDa
Purification:Affinity purification
Form:Liquid
Synonyms:MRD27; SOX11; SRY (sex determining region Y) box 11; SRY related HMG box gene 11 ; SRY-box 11; Transcription factor SOX-11;

Applications

WB 1:500-1:2000,IHC 1:100-1:200,IF-P 1:100-1:200

Immunogen

A synthetic peptide of human SOX11

Target Background

Probably important in the developing nervous system. May also have a role in tissue modeling during development. Transcription factor that acts as a transcriptional activator (PubMed:24886874). Binds cooperatively with POU3F2/BRN2 or POU3F1/OCT6 to gene promoters, which enhances transcriptional activation (By similarity). Acts as a transcriptional activator of TEAD2 by binding to its gene promoter and first intron (By similarity). Plays a redundant role with SOX4 and SOX12 in cell survival of developing tissues such as the neural tube, branchial arches and somites, thereby contributing to organogenesis (By similarity).

Synonyms:MRD27; SOX11; SRY (sex determining region Y) box 11; SRY related HMG box gene 11 ; SRY-box 11; Transcription factor SOX-11;

Storage

Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.

Buffer

Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% New type preservative N and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.

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