SP17 Rabbit Monoclonal Antibody

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Catalog Number:MABN86953
Conjugate:Unconjugated
Size:100μL
Concentration:1mg/ml
Host:Rabbit
Isotype:IgG
Clone:Monoclonal
Immunogen:A synthetic peptide of human SP17
Reactivity:Human,Mouse,Rat
Applications:WB 1:1000-1:5000,ICC/IF 1:100-1:200,FC 1:50-1:200
Molecular Weight:Calculated MW:17 kDa; Observed MW:17 kDa
Purification:Affinity Purification
Form:Liquid
Synonyms:CT22; SP17; SP17-1

Applications

WB 1:1000-1:5000,ICC/IF 1:100-1:200,FC 1:50-1:200

Immunogen

A synthetic peptide of human SP17

Target Background

This gene encodes a protein present at the cell surface. The N-terminus has sequence similarity to human cAMP-dependent protein kinase A (PKA) type II alpha regulatory subunit (RIIa) while the C-terminus has an IQ calmodulin-binding motif. The central portion of the protein has carbohydrate binding motifs and likely functions in cell-cell adhesion. The protein was initially characterized by its involvement in the binding of sperm to the zona pellucida of the oocyte. Recent studies indicate that it is also involved in additional cell-cell adhesion functions such as immune cell migration and metastasis. A retrotransposed pseudogene is present on chromosome 10q22.[provided by RefSeq, Jan 2009]

Synonyms:CT22; SP17; SP17-1

Storage

Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.

Buffer

Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

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