SPOP Rabbit Monoclonal antibody

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Catalog Number:MABN02633
Conjugate:Unconjugated
Size:100μL
Concentration:1mg/ml
Host:Rabbit
Isotype:IgG
Clone:Monoclonal
Immunogen:A synthetic peptide of human SPOP
Reactivity:Human
Applications:WB 1:500-1:1000
Molecular Weight:Calculated MW: 42 kDa; Observed MW: 42 kDa
Purification:Affinity Purified
Form:Liquid
Synonyms:Speckle-type POZ protein; HIB homolog 1; Roadkill homolog 1

Applications

WB 1:500-1:1000

Immunogen

A synthetic peptide of human SPOP

Target Background

Inhibits IPF1/PDX1 transactivation of established target promoters, such as insulin, may be by recruiting a repressor complex (By similarity). In complex with CUL3, involved in ubiquitination of BMI1, H2AFY and DAXX, and probably also in ubiquitination and proteasomal degradation of Gli2 or Gli3.

Synonyms:Speckle-type POZ protein; HIB homolog 1; Roadkill homolog 1

Storage

Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.

Buffer

50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA

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