SPP1 Mouse Monoclonal Antibody

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Catalog Number:MABN81205
Conjugate:Unconjugated
Size:100μL
Concentration:1mg/ml
Host:Mouse
Isotype:Mouse IgG1
Clone:Monoclonal
Immunogen:Purified recombinant fragment of human SPP1 (AA: 167-314) expressed in E. Coli.
Reactivity:Human
Applications:IHC 1:200-1:400,ELISA 1:5000-1:20000
Molecular Weight:35.4kDa
Purification:Affinity Purification
Form:Liquid
Synonyms:OPN; BNSP; BSPI; ETA-1

Applications

IHC 1:200-1:400,ELISA 1:5000-1:20000

Immunogen

Purified recombinant fragment of human SPP1 (AA: 167-314) expressed in E. Coli.

Target Background

The protein encoded by this gene is involved in the attachment of osteoclasts to the mineralized bone matrix. The encoded protein is secreted and binds hydroxyapatite with high affinity. The osteoclast vitronectin receptor is found in the cell membrane and may be involved in the binding to this protein. This protein is also a cytokine that upregulates expression of interferon-gamma and interleukin-12. Several transcript variants encoding different isoforms have been found for this gene.

Synonyms:OPN; BNSP; BSPI; ETA-1

Storage

Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.

Buffer

Purified antibody in PBS with 0.05% sodium azide

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