Immunological Sciences

SQSTM1 Mouse Monoclonal Antibody

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Catalog Number:MABN81216
Conjugate:Unconjugated
Size:100μL
Concentration:1mg/ml
Host:Mouse
Isotype:Mouse IgG1
Clone:Monoclonal
Immunogen:Purified recombinant fragment of human SQSTM1 (AA: 232-356) expressed in E. Coli.
Reactivity:Human,Mouse,Rat,Rabbit,Monkey
Applications:WB 1:500-1:2000,IHC 1:200-1:1000,ICC 1:100-1:200,ELISA 1:5000-1:20000,FC 1:200-1:400
Molecular Weight:47.7kDa
Purification:Affinity Purification
Form:Liquid
Synonyms:p60; p62; A170; OSIL; PDB3; ZIP3; p62B

Applications

WB 1:500-1:2000,IHC 1:200-1:1000,ICC 1:100-1:200,ELISA 1:5000-1:20000,FC 1:200-1:400

Immunogen

Purified recombinant fragment of human SQSTM1 (AA: 232-356) expressed in E. Coli.

Target Background

This gene encodes a multifunctional protein that binds ubiquitin and regulates activation of the nuclear factor kappa-B (NF-kB) signaling pathway. The protein functions as a scaffolding/adaptor protein in concert with TNF receptor-associated factor 6 to mediate activation of NF-kB in response to upstream signals. Alternatively spliced transcript variants encoding either the same or different isoforms have been identified for this gene. Mutations in this gene result in sporadic and familial Paget disease of bone.

Synonyms:p60; p62; A170; OSIL; PDB3; ZIP3; p62B

Storage

Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.

Buffer

Purified antibody in PBS with 0.05% sodium azide

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