SRp55 Rabbit Polyclonal Antibody

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Catalog Number:ABN18280
Conjugate:Unconjugated
Size:100μL
Concentration:1mg/ml
Host:Rabbit
Isotype:IgG
Clone:Polyclonal
Immunogen:Synthesized peptide derived from SRp55 . at AA range: 30-110
Reactivity:Human,Mouse,Rat
Applications:IHC 1:100-1:300,ICC/IF 1:50-1:200,ELISA 1:10000-1:20000
Purification:Affinity purification
Form:Liquid
Synonyms:SRSF6; SFRS6; SRP55; Serine/arginine-rich splicing factor 6; Pre-mRNA-splicing factor SRP55; Splicing factor; arginine/serine-rich 6

Applications

IHC 1:100-1:300,ICC/IF 1:50-1:200,ELISA 1:10000-1:20000

Immunogen

Synthesized peptide derived from SRp55 . at AA range: 30-110

Target Background

The protein encoded by this gene is involved in mRNA splicing and may play a role in the determination of alternative splicing. The encoded nuclear protein belongs to the splicing factor SR family and has been shown to bind with and modulate another member of the family, SFRS12. Alternative splicing results in multiple transcript variants. In addition, two pseudogenes, one on chromosome 17 and the other on the X chromosome, have been found for this gene.[provided by RefSeq, Sep 2010],function:Plays a role in constitutive splicing and can modulate the selection of alternative splice sites.,PTM:Extensively phosphorylated on serine residues in the RS domain.,similarity:Belongs to the splicing factor SR family.,similarity:Contains 2 RRM (RNA recognition motif) domains.,subunit:Binds SFRS12.,

Synonyms:SRSF6; SFRS6; SRP55; Serine/arginine-rich splicing factor 6; Pre-mRNA-splicing factor SRP55; Splicing factor; arginine/serine-rich 6

Storage

Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.

Buffer

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.

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