Immunological Sciences

SSTR2 Rabbit Polyclonal Antibody

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Catalog Number:ABN18308
Conjugate:Unconjugated
Size:100μL
Concentration:1mg/ml
Host:Rabbit
Isotype:IgG
Clone:Polyclonal
Immunogen:The antiserum was produced against synthesized peptide derived from the Internal region of human SSTR2. AA range:220-270
Reactivity:Human,Mouse,Rat
Applications:WB 1:500-1:2000,ELISA 1:5000-1:20000
Molecular Weight:40kDa
Purification:Affinity purification
Form:Liquid
Synonyms:Somatostatin receptor type 2 (SS-2-R) (SS2-R) (SS2R) (SRIF-1)

Applications

WB 1:500-1:2000,ELISA 1:5000-1:20000

Immunogen

The antiserum was produced against synthesized peptide derived from the Internal region of human SSTR2. AA range:220-270

Target Background

Somatostatin acts at many sites to inhibit the release of many hormones and other secretory proteins. The biologic effects of somatostatin are probably mediated by a family of G protein-coupled receptors that are expressed in a tissue-specific manner. SSTR2 is a member of the superfamily of receptors having seven transmembrane segments and is expressed in highest levels in cerebrum and kidney. [provided by RefSeq, Jul 2008],function:Receptor for somatostatins-14 and -28. This receptor is coupled via pertussis toxin sensitive G proteins to inhibition of adenylyl cyclase. In addition it stimulates phosphotyrosine phosphatase and PLC via pertussis toxin insensitive as well as sensitive G proteins. In RIN-5F cells, this receptor inhibits calcium entry by suppressing voltage dependent calcium-channels.,similarity:Belongs to the G-protein coupled receptor 1 family.,subunit:The C-terminus interacts with SHANK1 PDZ domain.,tissue specificity:Cerebrum and kidney. In lesser amounts in jejunum, colon and liver.,

Synonyms:Somatostatin receptor type 2 (SS-2-R) (SS2-R) (SS2R) (SRIF-1)

Storage

Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.

Buffer

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.

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