Immunological Sciences

STARD4 Rabbit Monoclonal Antibody

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Catalog Number:MABN21241
Conjugate:Unconjugated
Size:100μL
Concentration:1mg/ml
Host:Rabbit
Isotype:IgG,Kappa
Clone:Monoclonal
Immunogen:Recombinant protein of human STARD4
Reactivity:Human
Applications:WB 1:1000-1:5000,ICC/IF 1:100-1:300
Molecular Weight:CalcuLated MW:;Observed MW:23kD
Purification:Protein A
Form:Liquid
Synonyms:STARD4;StAR-related lipid transfer protein 4 ;START domain-containing protein 4;StARD4;

Applications

WB 1:1000-1:5000,ICC/IF 1:100-1:300

Immunogen

Recombinant protein of human STARD4

Target Background

Cholesterol homeostasis is regulated, at least in part, by sterol regulatory element (SRE)-binding proteins (e.g., SREBP1; MIM 184756) and by liver X receptors (e.g., LXRA; MIM 602423). Upon sterol depletion, LXRs are inactive and SREBPs are cleaved, after which they bind promoter SREs and activate genes involved in cholesterol biosynthesis and uptake. Sterol transport is mediated by vesicles or by soluble protein carriers, such as steroidogenic acute regulatory protein (STAR; MIM 600617). STAR is homologous to a family of proteins containing a 200- to 210-amino acid STAR-related lipid transfer (START) domain, including STARD4 (Soccio et al., 2002 [PubMed 12011452]).[supplied by OMIM, Mar 2008]

Synonyms:STARD4;StAR-related lipid transfer protein 4 ;START domain-containing protein 4;StARD4;

Storage

Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.

Buffer

PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA

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