STAT4 Rabbit Monoclonal Antibody

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Catalog Number:MABN83845
Conjugate:Unconjugated
Size:100μL
Concentration:1mg/ml
Host:Rabbit
Isotype:IgG
Clone:Monoclonal
Immunogen:A synthesized peptide derived from human STAT4
Reactivity:Human
Applications:WB 1:1000-1:2000,IHC 1:100-1:200,ICC/IF 1:50-1:200,ICC 1:50-1:200,FC 1:20-1:100,IP 1:20-1:50
Molecular Weight:86 kDa
Purification:Affinity Purification
Form:Liquid
Synonyms:Signal transducer and activator of transcription 4; Stat-4; Stat 4;;STAT4

Applications

WB 1:1000-1:2000,IHC 1:100-1:200,ICC/IF 1:50-1:200,ICC 1:50-1:200,FC 1:20-1:100,IP 1:20-1:50

Immunogen

A synthesized peptide derived from human STAT4

Target Background

Transcriptional regulator mainly expressed in hematopoietic cells that plays a critical role in cellular growth, differentiation and immune response .Plays a key role in the differentiation of T-helper 1 cells and the production of interferon-gamma.Participates also in multiple neutrophil functions including chemotaxis and production of the neutrophil extracellular traps (By similarity).After IL12 binding to its receptor IL12RB2, STAT4 interacts with the intracellular domain of IL12RB2 and becomes tyrosine phosphorylated.

Synonyms:Signal transducer and activator of transcription 4; Stat-4; Stat 4;;STAT4

Storage

Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.

Buffer

Purified antibody in PBS with 0.05% sodium azide,0.05% BSA and 50% glycerol.

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