STAT5a (1Y19) Rabbit Monoclonal Antibody

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Catalog Number:MABN18361
Conjugate:Unconjugated
Size:100μL
Concentration:1mg/ml
Host:Rabbit
Isotype:IgG
Clone:Monoclonal
Immunogen:A synthetic peptide of human STAT5a
Reactivity:Human,Mouse,Rat
Applications:WB 1:500-1:2000,IHC 1:200-1:1000,ICC/IF 1:100-1:500,FC 1:50-1:200,IP 1:20-1:50
Molecular Weight:91kDa
Purification:Affinity purification
Form:Liquid
Synonyms:MGF; MPF; Mammary gland factor; STA5A; STAT5; STAT5A

Applications

WB 1:500-1:2000,IHC 1:200-1:1000,ICC/IF 1:100-1:500,FC 1:50-1:200,IP 1:20-1:50

Immunogen

A synthetic peptide of human STAT5a

Target Background

The protein encoded by this gene is a member of the STAT family of transcription factors. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. Carries out a dual function: signal transduction and activation of transcription. Mediates cellular responses to the cytokine KITLG/SCF and other growth factors. Mediates cellular responses to ERBB4. May mediate cellular responses to activated FGFR1, FGFR2, FGFR3 and FGFR4. Binds to the GAS element and activates PRL- induced transcription. Regulates the expression of milk proteins during lactation.

Synonyms:MGF; MPF; Mammary gland factor; STA5A; STAT5; STAT5A

Storage

Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.

Buffer

Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% New type preservative N and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.

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