Immunological Sciences

STING Rabbit Monoclonal Antibody

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Catalog Number:MABN86574
Conjugate:Unconjugated
Size:100μL
Concentration:1mg/ml
Host:Rabbit
Isotype:IgG
Clone:Monoclonal
Immunogen:Recombinant protein of human STING
Reactivity:Human
Applications:WB 1:500-1:2000,IHC 1:500-1:2000,ICC/IF 1:100-1:200,FC 1:200-1:500,IP 1:20-1:50
Molecular Weight:Calculated MW:42 kDa; Observed MW:38 kDa
Purification:Affinity Purification
Form:Liquid
Synonyms:ERIS; MITA; MPYS; SAVI; NET23; STING; hMITA; hSTING; TMEM173; STING-beta

Applications

WB 1:500-1:2000,IHC 1:500-1:2000,ICC/IF 1:100-1:200,FC 1:200-1:500,IP 1:20-1:50

Immunogen

Recombinant protein of human STING

Target Background

This gene encodes a five transmembrane protein that functions as a major regulator of the innate immune response to viral and bacterial infections. The encoded protein is a pattern recognition receptor that detects cytosolic nucleic acids and transmits signals that activate type I interferon responses. The encoded protein has also been shown to play a role in apoptotic signaling by associating with type II major histocompatibility complex. Mutations in this gene are the cause of infantile-onset STING-associated vasculopathy. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Sep 2014]

Synonyms:ERIS; MITA; MPYS; SAVI; NET23; STING; hMITA; hSTING; TMEM173; STING-beta

Storage

Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.

Buffer

Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

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