Stromal Interaction Molecule 1 Rabbit Polyclonal Antibody

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Catalog Number:ABN00116
Conjugate:Unconjugated
Size:100μL
Concentration:1mg/ml
Host:Rabbit
Isotype:IgG
Clone:Polyclonal
Immunogen:A synthetic peptide of human Stromal interaction molecule 1
Reactivity:Human,Mouse,Rat
Applications:WB 1:500-1:1000,IHC 1:50-1:100,IP 1:20-1:50
Molecular Weight:Calculated MW: 77 kDa; Observed MW: 77 kDa
Purification:Affinity Chromatography
Form:Liquid
Synonyms:GOK; TAM; TAM1; IMD10; STRMK; D11S4896E

Applications

WB 1:500-1:1000,IHC 1:50-1:100,IP 1:20-1:50

Immunogen

A synthetic peptide of human Stromal interaction molecule 1

Target Background

STIM1 is a potential tumor suppressor; defects in STIM1 may cause rhabdomyosarcoma and rhabdoid tumors. STIM1 can either homodimerize or form heterodimers with STIM2. STIM2 possesses a high sequence identity to STIM1 and can function as an inhibitor of STIM1-mediated plasma membrane store-operated Ca2+ entry. However, further investigation is required to elucidate the true physiological function of STIM2.

Synonyms:GOK; TAM; TAM1; IMD10; STRMK; D11S4896E

Storage

Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.

Buffer

Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

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