SUN2 Rabbit Monoclonal Antibody

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Catalog Number:MABN86251
Conjugate:Unconjugated
Size:100μL
Concentration:1mg/ml
Host:Rabbit
Isotype:IgG
Clone:Monoclonal
Immunogen:A synthetic peptide of human SUN2
Reactivity:Human,Mouse,Rat
Applications:WB 1:1000-1:5000,IHC 1:200-1:1000,ICC/IF 1:200-1:2000,FC 1:20-1:50
Molecular Weight:Calculated MW:80 kDa; Observed MW:80 kDa
Purification:Affinity Purification
Form:Liquid
Synonyms:UNC84B

Applications

WB 1:1000-1:5000,IHC 1:200-1:1000,ICC/IF 1:200-1:2000,FC 1:20-1:50

Immunogen

A synthetic peptide of human SUN2

Target Background

SUN1 (MIM 607723) and SUN2 are inner nuclear membrane (INM) proteins that play a major role in nuclear-cytoplasmic connection by formation of a 'bridge' across the nuclear envelope, known as the LINC complex, via interaction with the conserved luminal KASH domain of nesprins (e.g., SYNE1; MIM 608441) located in the outer nuclear membrane (ONM). The LINC complex provides a direct connection between the nuclear lamina and the cytoskeleton, which contributes to nuclear positioning and cellular rigidity (summary by Haque et al., 2010 [PubMed 19933576]).[supplied by OMIM, Nov 2010]

Synonyms:UNC84B

Storage

Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.

Buffer

Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

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