Superoxide Dismutase 1 Rabbit Monoclonal Antibody

No images available

Catalog Number:MABN03217
Conjugate:Unconjugated
Size:100μL
Concentration:1mg/ml
Host:Rabbit
Isotype:IgG
Clone:Monoclonal
Immunogen:Recombinant protein of human Superoxide Dismutase 1
Reactivity:Human
Applications:WB 1:500-1:1000,IHC 1:50-1:100,ICC/IF 1:50-1:200
Molecular Weight:Calculated MW: 16 kDa; Observed MW: 16 kDa
Purification:Affinity Purification
Form:Liquid
Synonyms:SOD1; Superoxide dismutase [Cu-Zn]; Superoxide dismutase 1; hSod1

Applications

WB 1:500-1:1000,IHC 1:50-1:100,ICC/IF 1:50-1:200

Immunogen

Recombinant protein of human Superoxide Dismutase 1

Target Background

SOD1, Cu/Zn superoxide dismutase, is a major antioxidant enzyme that catalyzes the conversion of superoxide anion to hydrogen peroxide and molecular oxygen. The mechanism by which mutant SOD1 induces the neurodegeneration observed in ALS is still unclear. Mutant SOD1 proteins become misfolded and consequently oligomerize into high molecular weight species that aggregate and end up in proteinaceous inclusions.

Synonyms:SOD1; Superoxide dismutase [Cu-Zn]; Superoxide dismutase 1; hSod1

Storage

Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.

Buffer

50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA

No documents available.