Immunological Sciences

Superoxide Dismutase 1 Rabbit Polyclonal Antibody

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Catalog Number:ABN00451
Conjugate:Unconjugated
Size:100μL
Concentration:1mg/ml
Host:Rabbit
Isotype:IgG
Clone:Polyclonal
Immunogen:Recombinant protein of human Superoxide Dismutase 1
Reactivity:Human,Mouse,Rat
Applications:WB 1:500-1:1000,IHC 1:50-1:100
Molecular Weight:Calculated MW: 16 kDa; Observed MW: 16 kDa
Purification:Affinity Purification
Form:Liquid
Synonyms:SOD1; Superoxide dismutase [Cu-Zn]; Superoxide dismutase 1; hSod1

Applications

WB 1:500-1:1000,IHC 1:50-1:100

Immunogen

Recombinant protein of human Superoxide Dismutase 1

Target Background

SOD1, Cu/Zn superoxide dismutase, is a major antioxidant enzyme that catalyzes the conversion of superoxide anion to hydrogen peroxide and molecular oxygen. The mechanism by which mutant SOD1 induces the neurodegeneration observed in ALS is still unclear. Mutant SOD1 proteins become misfolded and consequently oligomerize into high molecular weight species that aggregate and end up in proteinaceous inclusions.

Synonyms:SOD1; Superoxide dismutase [Cu-Zn]; Superoxide dismutase 1; hSod1

Storage

Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.

Buffer

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3.

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