Syntaxin 1A Rabbit Monoclonal Antibody
Western blot analysis of extracts from Mouse brain tissue using Syntaxin 1A Rabbit Monoclonal Antibody at 1:1000.
| Catalog Number: | MABN87650 |
| Conjugate: | Unconjugated |
| Size: | 100ul |
| Concentration: | 1mg/ml |
| Host: | Rabbit |
| Isotype: | IgG |
| Clone: | Monoclonal |
| Immunogen: | Recombinant protein of human Syntaxin 1A |
| Reactivity: | Human,Mouse,Rat |
| Applications: | WB 1:500-1:2000,IHC 1:200-1:2000,ICC/IF 1:20-1:50,FC 1:200-1:500,IP 1:20-1:50 |
| Molecular Weight: | 33 kDa |
| Purification: | Affinity purification |
| Form: | Liquid |
| Synonyms: | STX1; HPC-1; P35-1; SYN1A |
This gene encodes a member of the syntaxin superfamily. Syntaxins are nervous system-specific proteins implicated in the docking of synaptic vesicles with the presynaptic plasma membrane. Syntaxins possess a single C-terminal transmembrane domain, a SNARE [Soluble NSF (N-ethylmaleimide-sensitive fusion protein)-Attachment protein REceptor] domain (known as H3), and an N-terminal regulatory domain (Habc). Syntaxins bind synaptotagmin in a calcium-dependent fashion and interact with voltage dependent calcium and potassium channels via the C-terminal H3 domain. This gene product is a key molecule in ion channel regulation and synaptic exocytosis. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Sep 2009]
Applications
WB 1:500-1:2000,IHC 1:200-1:2000,ICC/IF 1:20-1:50,FC 1:200-1:500,IP 1:20-1:50
Immunogen
Recombinant protein of human Syntaxin 1A