TARDBP Mouse Monoclonal Antibody
Black line: Control Antigen (100 ng); Purple line: Antigen(10ng); Blue line: Antigen (50 ng); Red line: Antigen (100 ng);
| Catalog Number: | MABN81511 |
| Conjugate: | Unconjugated |
| Size: | 100ul |
| Concentration: | 1mg/ml |
| Host: | Mouse |
| Isotype: | Mouse IgG1 |
| Clone: | Monoclonal |
| Immunogen: | Purified recombinant fragment of human TARDBP (AA: 126-260) expressed in E. Coli. |
| Reactivity: | Human |
| Applications: | ELISA 1:5000-1:20000,FC 1:200-1:400 |
| Molecular Weight: | 7kDa |
| Purification: | Affinity purification |
| Form: | liquid |
| Synonyms: | ALS10; TDP-43 |
HIV-1, the causative agent of acquired immunodeficiency syndrome (AIDS), contains an RNA genome that produces a chromosomally integrated DNA during the replicative cycle. Activation of HIV-1 gene expression by the transactivator Tat is dependent on an RNA regulatory element (TAR) located downstream of the transcription initiation site. The protein encoded by this gene is a transcriptional repressor that binds to chromosomally integrated TAR DNA and represses HIV-1 transcription. In addition, this protein regulates alternate splicing of the CFTR gene. A similar pseudogene is present on chromosome 20.
Applications
ELISA 1:5000-1:20000,FC 1:200-1:400
Immunogen
Purified recombinant fragment of human TARDBP (AA: 126-260) expressed in E. Coli.
