TBX21 Rabbit Monoclonal Antibody

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Catalog Number:MABN84511
Conjugate:Unconjugated
Size:100μL
Concentration:1mg/ml
Host:Rabbit
Isotype:IgG
Clone:Monoclonal
Immunogen:A synthesized peptide derived from human TBX21
Reactivity:Human
Applications:IHC 1:100-1:200,FC 1:20-1:100
Molecular Weight:58 kDa
Purification:Affinity Purification
Form:Liquid
Synonyms:T bet; T box 21; T PET; TBET; TBLYM; Tbx21; TPET; Transcription factor TBLYM;;TBX21

Applications

IHC 1:100-1:200,FC 1:20-1:100

Immunogen

A synthesized peptide derived from human TBX21

Target Background

Lineage-defining transcription factor which initiates Th1 lineage development from naive Th precursor cells both by activating Th1 genetic programs and by repressing the opposing Th2 and Th17 genetic programs.Activates transcription of a set of genes important for Th1 cell function, including those encoding IFN-gamma and the chemokine receptor CXCR3. Induces permissive chromatin accessibilty and CpG methylation in IFNG.

Synonyms:T bet; T box 21; T PET; TBET; TBLYM; Tbx21; TPET; Transcription factor TBLYM;;TBX21

Storage

Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.

Buffer

Purified antibody in PBS with 0.05% sodium azide,0.05% BSA and 50% glycerol.

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