TCEA1 Rabbit Monoclonal Antibody

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Catalog Number:MABN86919
Conjugate:Unconjugated
Size:100μL
Concentration:1mg/ml
Host:Rabbit
Isotype:IgG
Clone:Monoclonal
Immunogen:A synthetic peptide of human TCEA1
Reactivity:Human,Mouse,Rat
Applications:WB 1:1000-1:5000,IHC 1:200-1:500,ICC/IF 1:200-1:500,FC 1:100-1:200,IP 1:20-1:50
Molecular Weight:Calculated MW:34 kDa; Observed MW:37 kDa
Purification:Affinity Purification
Form:Liquid
Synonyms:SII; TCEA; TF2S; GTF2S; TFIIS

Applications

WB 1:1000-1:5000,IHC 1:200-1:500,ICC/IF 1:200-1:500,FC 1:100-1:200,IP 1:20-1:50

Immunogen

A synthetic peptide of human TCEA1

Target Background

Necessary for efficient RNA polymerase II transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by S-II allows the resumption of elongation from the new 3'-terminus.

Synonyms:SII; TCEA; TF2S; GTF2S; TFIIS

Storage

Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.

Buffer

Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

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