TDP 43 Rabbit Monoclonal Antibody

Immunocytochemistry analysis of TDP 43 (green) in 293t using TDP 43 antibody,and DAPI(blue).

Immunocytochemistry analysis of TDP 43 (green) in 293t using TDP 43 antibody,and DAPI(blue).

Catalog Number:MABN02677
Conjugate:Unconjugated
Size:100μL
Concentration:1mg/ml
Host:Rabbit
Isotype:IgG
Clone:Monoclonal
Immunogen:A synthetic peptide of human TDP43
Reactivity:Human,Mouse,Rat
Applications:WB 1:500-1:1000,IHC 1:50-1:100,ICC/IF 1:50-1:200,IP 1:20-1:50
Molecular Weight:45 kDa
Purification:Affinity purification
Form:liquid
Synonyms:ALS10; TDP-43

TDP43 (TAR DNA-binding protein 43) is involved in transcriptional regulation and exon splicing. While normal TDP43 is a nuclear protein, pathological TDP43 is a component of insoluble aggregates in patients with frontotemporal lobar degeneration (FTLD) and amyotrophic lateral sclerosis (ALS).

Applications

WB 1:500-1:1000,IHC 1:50-1:100,ICC/IF 1:50-1:200,IP 1:20-1:50

Immunogen

A synthetic peptide of human TDP43

Target Background

TDP43 (TAR DNA-binding protein 43) is involved in transcriptional regulation and exon splicing. While normal TDP43 is a nuclear protein, pathological TDP43 is a component of insoluble aggregates in patients with frontotemporal lobar degeneration (FTLD) and amyotrophic lateral sclerosis (ALS).

Synonyms:ALS10; TDP-43

Storage

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Buffer

50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% protective protein

Immunocytochemistry analysis of TDP 43 (green) in 293t using TDP 43 antibody,and DAPI(blue).

Immunohistochemistry analysis of paraffin-embedded Human brain using TDP 43 antibody.High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval.

Western blot analysis of TDP43 in K562, C6, 3T3, Hela lysates using TDP43 antibody

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