Tenascin C (7E16) Rabbit Monoclonal Antibody
Western blot analysis of Cytotactin C expression in (1)Human fetal brain lysate; (2)Human fetal kidney lysate.
| Catalog Number: | MABN18788 |
| Conjugate: | Unconjugated |
| Size: | 100ul |
| Concentration: | 1mg/ml |
| Host: | Rabbit |
| Isotype: | IgG |
| Clone: | 7E16 |
| Immunogen: | A synthetic peptide of human Tenascin C |
| Reactivity: | Human,Mouse,Rat |
| Applications: | WB 1:1000-1:5000,IHC 1:200-1:500,IF-P 1:200-1:500 |
| Molecular Weight: | 241kDa |
| Purification: | Affinity purification |
| Form: | Liquid |
| Synonyms: | Tenascin; TN; Cytotactin; GMEM; GP 150-225; Glioma-associated-extracellular matrix antigen; Hexabrachion; JI; Myotendinous antigen; Neuronectin; Tenascin C; TN-C; TNC; HXB |
The tenascin family of extracellular matrix proteins includes Tenascin-C (also designated cytotactin or Tenascin), Tenascin-R (also designated restrictin, TN-R or janusin) and Tenascin-X. Tenascin proteins function as substrate-adhesion molecules (SAMs) and are involved in regulating numerous developmental processes, such as morphogenetic cell migration and organogenesis. The tenascin family proteins arise from various splicing events in the region of coding for FNIII repeats. Extracellular matrix protein implicated in guidance of migrating neurons as well as axons during development, synaptic plasticity as well as neuronal regeneration. Promotes neurite outgrowth from cortical neurons grown on a monolayer of astrocytes. Ligand for integrins alpha-8/beta-1, alpha-9/beta-1, alpha-V/beta-3 and alpha- V/beta-6. In tumors, stimulates angiogenesis by elongation, migration and sprouting of endothelial cells (PubMed:19884327).
Applications
WB 1:1000-1:5000,IHC 1:200-1:500,IF-P 1:200-1:500
Immunogen
A synthetic peptide of human Tenascin C