Immunological Sciences

Tensin-2 Rabbit Polyclonal Antibody

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Catalog Number:ABN18794
Conjugate:Unconjugated
Size:100μL
Concentration:1mg/ml
Host:Rabbit
Isotype:IgG
Clone:Polyclonal
Immunogen:The antiserum was produced against synthesized peptide derived from human Tensin-2. AA range:439-488
Reactivity:Human,Mouse
Applications:WB 1:500-1:2000,ELISA 1:5000-1:20000
Molecular Weight:125kDa
Purification:Affinity purification
Form:Liquid
Synonyms:TENC1; KIAA1075; TNS2; Tensin-like C1 domain-containing phosphatase; C1 domain-containing phosphatase and tensin homolog; C1-TEN; Tensin-2

Applications

WB 1:500-1:2000,ELISA 1:5000-1:20000

Immunogen

The antiserum was produced against synthesized peptide derived from human Tensin-2. AA range:439-488

Target Background

The protein encoded by this gene belongs to the tensin family. Tensin is a focal adhesion molecule that binds to actin filaments and participates in signaling pathways. This protein plays a role in regulating cell migration. Alternative splicing occurs at this locus and three transcript variants encoding three distinct isoforms have been identified. [provided by RefSeq, Jul 2008],function:Regulates cell motility and proliferation. May have phosphatase activity. Reduces AKT1 phosphorylation. Lowers AKT1 kinase activity and interferes with AKT1 signaling.,similarity:Contains 1 C2 tensin-type domain.,similarity:Contains 1 phorbol-ester/DAG-type zinc finger.,similarity:Contains 1 phosphatase tensin-type domain.,similarity:Contains 1 SH2 domain.,subcellular location:Detected at the end of actin stress fibers.,subunit:Interacts with AXL.,tissue specificity:Detected in heart, kidney, brain, thymus, spleen, liver, placenta, lung, skeletal muscle and small intestine.,

Synonyms:TENC1; KIAA1075; TNS2; Tensin-like C1 domain-containing phosphatase; C1 domain-containing phosphatase and tensin homolog; C1-TEN; Tensin-2

Storage

Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.

Buffer

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.

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