Thrombomodulin Rabbit Monoclonal Antibody

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Catalog Number:MABN02687
Conjugate:Unconjugated
Size:100μL
Concentration:1mg/ml
Host:Rabbit
Isotype:IgG
Clone:Monoclonal
Immunogen:Recombinant protein of mouse Thrombomodulin
Reactivity:Mouse,Rat
Applications:WB 1:500-1:1000
Molecular Weight:Calculated MW: 62 kDa; Observed MW: 95 kDa
Purification:Affinity Purification
Form:Liquid
Synonyms:CD141; Fetomodulin; THBD; THRM; thrombomodulin; TM

Applications

WB 1:500-1:1000

Immunogen

Recombinant protein of mouse Thrombomodulin

Target Background

Thrombomodulin is a specific endothelial cell receptor that forms a 1:1 stoichiometric complex with thrombin. This complex is responsible for the conversion of protein C to the activated protein C (protein Ca). Once evolved, protein Ca scissions the activated cofactors of the coagulation mechanism, factor Va and factor VIIIa, and thereby reduces the amount of thrombin generated.

Synonyms:CD141; Fetomodulin; THBD; THRM; thrombomodulin; TM

Storage

Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.

Buffer

50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA

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