Immunological Sciences

Thrombopoietin Rabbit Monoclonal Antibody

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Catalog Number:MABN86620
Conjugate:Unconjugated
Size:100μL
Concentration:1mg/ml
Host:Rabbit
Isotype:IgG
Clone:Monoclonal
Immunogen:Recombinant protein of human Thrombopoietin
Reactivity:Human
Applications:WB 1:1000-1:5000,IHC 1:500-1:2000,ICC/IF 1:20-1:50,FC 1:20-1:50
Molecular Weight:Calculated MW:38 kDa; Observed MW:38 kDa
Purification:Affinity Purification
Form:Liquid
Synonyms:ML; TPO; MGDF; MKCSF; MPLLG; THCYT1

Applications

WB 1:1000-1:5000,IHC 1:500-1:2000,ICC/IF 1:20-1:50,FC 1:20-1:50

Immunogen

Recombinant protein of human Thrombopoietin

Target Background

Megakaryocytopoiesis is the cellular development process that leads to platelet production. The main functional protein encoded by this gene is a humoral growth factor that is necessary for megakaryocyte proliferation and maturation, as well as for thrombopoiesis. This protein is the ligand for MLP/C_MPL, the product of myeloproliferative leukemia virus oncogene. Mutations in this gene are the cause of thrombocythemia 1. Alternative promoter usage and differential splicing result in multiple transcript variants differing in the 5' UTR and/or coding region. Multiple AUG codons upstream of the main open reading frame (ORF) have been identified, and these upstream AUGs inhibit translation of the main ORF at different extent. [provided by RefSeq, Feb 2014]

Synonyms:ML; TPO; MGDF; MKCSF; MPLLG; THCYT1

Storage

Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.

Buffer

Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

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