Immunological Sciences

TIE1 Mouse Monoclonal Antibody

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Catalog Number:MABN81319
Conjugate:Unconjugated
Size:100μL
Concentration:1mg/ml
Host:Mouse
Isotype:Mouse IgG1
Clone:Monoclonal
Immunogen:Purified recombinant fragment of human TIE1 (AA: 385-607) expressed in E. Coli.
Reactivity:Human
Applications:IHC 1:200-1:1000,ELISA 1:5000-1:20000
Molecular Weight:125kDa
Purification:Affinity Purification
Form:Liquid
Synonyms:TIE; JTK14

Applications

IHC 1:200-1:1000,ELISA 1:5000-1:20000

Immunogen

Purified recombinant fragment of human TIE1 (AA: 385-607) expressed in E. Coli.

Target Background

This gene encodes a member of the tyrosine protein kinase family. The encoded protein plays a critical role in angiogenesis and blood vessel stability by inhibiting angiopoietin 1 signaling through the endothelial receptor tyrosine kinase Tie2. Ectodomain cleavage of the encoded protein relieves inhibition of Tie2 and is mediated by multiple factors including vascular endothelial growth factor. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.

Synonyms:TIE; JTK14

Storage

Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.

Buffer

Purified antibody in PBS with 0.05% sodium azide.

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