TIM3 Mouse Monoclonal Antibody

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Catalog Number:MABN81997
Conjugate:Unconjugated
Size:100μL
Concentration:1mg/ml
Host:Mouse
Isotype:Mouse IgG1
Clone:Monoclonal
Immunogen:Purified recombinant fragment of human TIM3 (AA: extra 22-202) expressed in HEK293 cells.
Reactivity:Human
Applications:ICC 1:200-1:1000,ELISA 1:5000-1:20000,FC 1:200-1:400
Molecular Weight:33.4kDa
Purification:Affinity Purification
Form:Liquid
Synonyms:HAVCR2; CD366; KIM-3; TIMD3; Tim-3; TIMD-3; HAVcr-2

Applications

ICC 1:200-1:1000,ELISA 1:5000-1:20000,FC 1:200-1:400

Immunogen

Purified recombinant fragment of human TIM3 (AA: extra 22-202) expressed in HEK293 cells.

Target Background

The protein encoded by this gene belongs to the immunoglobulin superfamily, and TIM family of proteins. CD4-positive T helper lymphocytes can be divided into types 1 (Th1) and 2 (Th2) on the basis of their cytokine secretion patterns. Th1 cells are involved in cell-mediated immunity to intracellular pathogens and delayed-type hypersensitivity reactions, whereas, Th2 cells are involved in the control of extracellular helminthic infections and the promotion of atopic and allergic diseases. This protein is a Th1-specific cell surface protein that regulates macrophage activation, and inhibits Th1-mediated auto- and alloimmune responses, and promotes immunological tolerance.

Synonyms:HAVCR2; CD366; KIM-3; TIMD3; Tim-3; TIMD-3; HAVcr-2

Storage

Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.

Buffer

Purified antibody in PBS with 0.05% sodium azide

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