Timeless Rabbit Monoclonal Antibody

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Catalog Number:MABN84566
Conjugate:Unconjugated
Size:100μL
Concentration:1mg/ml
Host:Rabbit
Isotype:IgG
Clone:Monoclonal
Immunogen:A synthesized peptide derived from human Timeless
Reactivity:Human
Applications:WB 1:1000-1:2000,IHC 1:100-1:200,ICC/IF 1:50-1:200,ICC 1:50-1:200
Molecular Weight:Calculated MW: 139 kDa ; Observed MW: 150 kDa
Purification:Affinity Purification
Form:Liquid
Synonyms:hTIM; TIM; TIM1; Timeless; timeless circadian clock 1; TIMELESS1;;Timeless

Applications

WB 1:1000-1:2000,IHC 1:100-1:200,ICC/IF 1:50-1:200,ICC 1:50-1:200

Immunogen

A synthesized peptide derived from human Timeless

Target Background

Plays an important role in the control of DNA replication, maintenance of replication fork stability, maintenance of genome stability throughout normal DNA replication, DNA repair and in the regulation of the circadian clock.Required to stabilize replication forks during DNA replication by forming a complex with TIPIN: this complex regulates DNA replication processes under both normal and stress conditions, stabilizes replication forks and influences both CHEK1 phosphorylation and the intra-S phase checkpoint in response to genotoxic stress.

Synonyms:hTIM; TIM; TIM1; Timeless; timeless circadian clock 1; TIMELESS1;;Timeless

Storage

Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.

Buffer

Purified antibody in PBS with 0.05% sodium azide,0.05% BSA and 50% glycerol.

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