Immunological Sciences

TIMP-4 Rabbit Polyclonal Antibody

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Catalog Number:ABN18954
Conjugate:Unconjugated
Size:100μL
Concentration:1mg/ml
Host:Rabbit
Isotype:IgG
Clone:Polyclonal
Immunogen:Synthesized peptide derived from TIMP-4 at AA range: 174-223
Reactivity:Human,Rat,Mouse
Applications:WB 1:500-1:2000,IHC 1:50-1:300,ELISA 1:2000-1:20000
Molecular Weight:26kDa
Purification:Affinity purification
Form:Liquid
Synonyms:Metalloproteinase inhibitor 4 (Tissue inhibitor of metalloproteinases 4) (TIMP-4)

Applications

WB 1:500-1:2000,IHC 1:50-1:300,ELISA 1:2000-1:20000

Immunogen

Synthesized peptide derived from TIMP-4 at AA range: 174-223

Target Background

This gene belongs to the TIMP gene family. The proteins encoded by this gene family are inhibitors of the matrix metalloproteinases, a group of peptidases involved in degradation of the extracellular matrix. The secreted, netrin domain-containing protein encoded by this gene is involved in regulation of platelet aggregation and recruitment and may play role in hormonal regulation and endometrial tissue remodeling. [provided by RefSeq, Jul 2008],function:Complexes with metalloproteinases (such as collagenases) and irreversibly inactivates them. Known to act on MMP-1, MMP-2, MMP-3, MMP-7 and MMP-9.,similarity:Belongs to the protease inhibitor I35 (TIMP) family.,similarity:Contains 1 NTR domain.,tissue specificity:Abundant in heart and present at low levels in many other tissues.,

Synonyms:Metalloproteinase inhibitor 4 (Tissue inhibitor of metalloproteinases 4) (TIMP-4)

Storage

Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.

Buffer

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.

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