TIMP1 Rabbit Monoclonal Antibody

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Catalog Number:MABN87792
Conjugate:Unconjugated
Size:100μL
Concentration:1mg/ml
Host:Rabbit
Isotype:IgG
Clone:Monoclonal
Immunogen:Recombinant protein of mouse TIMP1
Reactivity:Mouse
Applications:WB 1:500-1:2000
Molecular Weight:Calculated MW:23 kDa; Observed MW:26 kDa
Purification:Affinity Purification
Form:Liquid
Synonyms:EPA; Clgi; Timp; TIMP-1; TPA-S1

Applications

WB 1:500-1:2000

Immunogen

Recombinant protein of mouse TIMP1

Target Background

Metalloproteinase inhibitor that functions by forming one to one complexes with target metalloproteinases, such as collagenases, and irreversibly inactivates them by binding to their catalytic zinc cofactor. Acts on MMP1, MMP2, MMP3, MMP7, MMP8, MMP9, MMP10, MMP11, MMP12, MMP13 and MMP16. Does not act on MMP14 (By similarity). Also functions as a growth factor that regulates cell differentiation, migration and cell death and activates cellular signaling cascades via CD63 and ITGB1. Plays a role in integrin signaling.

Synonyms:EPA; Clgi; Timp; TIMP-1; TPA-S1

Storage

Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.

Buffer

Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

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