TIRAP Rabbit Monoclonal Antibody

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Catalog Number:MABN84311
Conjugate:Unconjugated
Size:100μL
Concentration:1mg/ml
Host:Rabbit
Isotype:IgG
Clone:Monoclonal
Immunogen:A synthesized peptide derived from human TIRAP
Reactivity:Human,Mouse,Rat
Applications:WB 1:1000-1:2000
Molecular Weight:Calculated MW: 24 kDa ; Observed MW: 28 kDa
Purification:Affinity Purification
Form:Liquid
Synonyms:MAL; Wyatt;;TIRAP

Applications

WB 1:1000-1:2000

Immunogen

A synthesized peptide derived from human TIRAP

Target Background

Adapter involved in TLR2, TLR4 and RAGE signaling pathways in the innate immune response. Acts via IRAK2 and TRAF-6, leading to the activation of NF-kappa-B, MAPK1, MAPK3 and JNK, and resulting in cytokine secretion and the inflammatory response. Positively regulates the production of TNF-alpha (TNF) and interleukin-6 (IL6).

Synonyms:MAL; Wyatt;;TIRAP

Storage

Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.

Buffer

Purified antibody in PBS with 0.05% sodium azide,0.05% BSA and 50% glycerol.

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