Immunological Sciences

TLN2 Rabbit Polyclonal Antibody

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Catalog Number:ABN18985
Conjugate:Unconjugated
Size:100μL
Concentration:1mg/ml
Host:Rabbit
Isotype:IgG
Clone:Polyclonal
Immunogen:Synthesized peptide derived from part region of human protein
Reactivity:Human,Mouse
Applications:IHC 1:50-1:300,ICC/IF 1:50-1:200
Molecular Weight:279kDa
Purification:Affinity purification
Form:Liquid

Applications

IHC 1:50-1:300,ICC/IF 1:50-1:200

Immunogen

Synthesized peptide derived from part region of human protein

Target Background

This gene encodes a protein related to talin 1, a cytoskeletal protein that plays a significant role in the assembly of actin filaments and in spreading and migration of various cell types, including fibroblasts and osteoclasts. This protein has a different pattern of expression compared to talin 1 but, like talin 1, is thought to associate with unique transmembrane receptors to form novel linkages between extracellular matrices and the actin cytoskeleton. [provided by RefSeq, Jul 2008],function:As a major component of focal adhesion plaques that links integrin to the actin cytoskeleton, may play an important role in cell adhesion. Recruits PIP5K1C to focal adhesion plaques and strongly activates its kinase activity.,similarity:Contains 1 FERM domain.,similarity:Contains 1 I/LWEQ domain.,subcellular location:Focal adhesion plaques and synapses.,subunit:Interacts directly with PIP5K1C.,

Storage

Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.

Buffer

Liquid in PBS containing 50% glycerol, and 0.02% New type preservative N.

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