Immunological Sciences

TLR9 Rabbit Monoclonal Antibody

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Catalog Number:MABN87025
Conjugate:Unconjugated
Size:100μL
Concentration:1mg/ml
Host:Rabbit
Isotype:IgG
Clone:Monoclonal
Immunogen:Recombinant protein of human TLR9
Reactivity:Human
Applications:WB 1:500-1:2000,IP 1:20-1:50
Molecular Weight:Calculated MW:116 kDa; Observed MW:130 kDa
Purification:Affinity Purification
Form:Liquid
Synonyms:CD289

Applications

WB 1:500-1:2000,IP 1:20-1:50

Immunogen

Recombinant protein of human TLR9

Target Background

The protein encoded by this gene is a member of the Toll-like receptor (TLR) family, which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. Studies in mice and human indicate that this receptor mediates cellular response to unmethylated CpG dinucleotides in bacterial DNA to mount an innate immune response. [provided by RefSeq, Aug 2017]

Synonyms:CD289

Storage

Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.

Buffer

Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

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