Immunological Sciences

TLS/FUS Rabbit Monoclonal Antibody

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Catalog Number:MABN86791
Conjugate:Unconjugated
Size:100μL
Concentration:1mg/ml
Host:Rabbit
Isotype:IgG
Clone:Monoclonal
Immunogen:A synthetic peptide of human TLS/FUS
Reactivity:Human
Applications:WB 1:500-1:2000,IHC 1:200-1:1000,ICC/IF 1:100-1:200,FC 1:50-1:200
Molecular Weight:Calculated MW:53 kDa; Observed MW:70 kDa
Purification:Affinity Purification
Form:Liquid
Synonyms:TLS; ALS6; ETM4; FUS1; POMP75; HNRNPP2

Applications

WB 1:500-1:2000,IHC 1:200-1:1000,ICC/IF 1:100-1:200,FC 1:50-1:200

Immunogen

A synthetic peptide of human TLS/FUS

Target Background

This gene encodes a multifunctional protein component of the heterogeneous nuclear ribonucleoprotein (hnRNP) complex. The hnRNP complex is involved in pre-mRNA splicing and the export of fully processed mRNA to the cytoplasm. This protein belongs to the FET family of RNA-binding proteins which have been implicated in cellular processes that include regulation of gene expression, maintenance of genomic integrity and mRNA/microRNA processing. Alternative splicing results in multiple transcript variants. Defects in this gene result in amyotrophic lateral sclerosis type 6. [provided by RefSeq, Sep 2009]

Synonyms:TLS; ALS6; ETM4; FUS1; POMP75; HNRNPP2

Storage

Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.

Buffer

Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

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