Immunological Sciences

TMEM173 Monoclonal Antibody

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Catalog Number:MAB-94702
Conjugate:Unconjugated
Size:100ug
Concentration:1mg/ml
Host:Rb
Isotype:IgG
Clone:EPR13130
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 150-379 of human STING/TMEM173 (NP_938023.1).
Reactivity:Human, Mouse, Rat
Applications:WB 1:10000 - 1:29000; IHC 1:100 - 1:500
Molecular Weight:42kDA
Purification:Aff. Pur.
Form:Liquid
Synonyms:TMEM173; ERIS; MITA; MPYS; NET23; SAVI; STING; hMITA; hSTING

Applications

WB 1:10000 - 1:29000; IHC 1:100 - 1:500

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 150-379 of human STING/TMEM173 (NP_938023.1).

Target Background

This gene encodes a five transmembrane protein that functions as a major regulator of the innate immune response to viral and bacterial infections. The encoded protein is a pattern recognition receptor that detects cytosolic nucleic acids and transmits signals that activate type I interferon responses. The encoded protein has also been shown to play a role in apoptotic signaling by associating with type II major histocompatibility complex. Mutations in this gene are the cause of infantile-onset STING-associated vasculopathy. Alternate splicing results in multiple transcript variants.

Synonyms:TMEM173; ERIS; MITA; MPYS; NET23; SAVI; STING; hMITA; hSTING

Storage

Store at -20℃. Avoid freeze / thaw cycles.

Buffer

Buffer: PBS with 0.05% proclin300, 0.05% BSA, 50% glycerol, pH7.3.

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