Immunological Sciences

TMEM173 Rabbit Monoclonal Antibody

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Catalog Number:MABN21585
Conjugate:Unconjugated
Size:100μL
Concentration:1mg/ml
Host:Rabbit
Isotype:IgG,Kappa
Clone:Monoclonal
Immunogen:Recombinant protein of human STING
Reactivity:Human,Mouse,Rat,
Applications:WB 1:1000-1:5000,IHC 1:200-1:1000,ICC/IF 1:200-1:1000,ELISA 1:5000-1:20000,IP 1:50-1:200
Molecular Weight:CalcuLated MW:42kD;Observed MW:37kD
Purification:Protein A
Form:Liquid
Synonyms:TMEM173;ERIS;MITA;STING;Transmembrane protein 173;Endoplasmic reticuLum interferon stimuLator;ERIS;Mediator of IRF3 activation;hMITA;StimuLator of interferon genes protein;hSTING

Applications

WB 1:1000-1:5000,IHC 1:200-1:1000,ICC/IF 1:200-1:1000,ELISA 1:5000-1:20000,IP 1:50-1:200

Immunogen

Recombinant protein of human STING

Target Background

Cell localization:Cytoplasmic, Membranous.This gene encodes a five transmembrane protein that functions as a major regulator of the innate immune response to viral and bacterial infections. The encoded protein is a pattern recognition receptor that detects cytosolic nucleic acids and transmits signals that activate type I interferon responses. The encoded protein has also been shown to play a role in apoptotic signaling by associating with type II major histocompatibility complex. Mutations in this gene are the cause of infantile-onset STING-associated vasculopathy. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Sep 2014],

Synonyms:TMEM173;ERIS;MITA;STING;Transmembrane protein 173;Endoplasmic reticuLum interferon stimuLator;ERIS;Mediator of IRF3 activation;hMITA;StimuLator of interferon genes protein;hSTING

Storage

Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.

Buffer

PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA

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