Immunological Sciences

TMPRSS2 Rabbit Monoclonal Antibody

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Catalog Number:MABN86929
Conjugate:Unconjugated
Size:100μL
Concentration:1mg/ml
Host:Rabbit
Isotype:IgG
Clone:Monoclonal
Immunogen:A synthetic peptide of human TMPRSS2
Reactivity:Human
Applications:WB 1:1000-1:5000,IHC 1:500-1:2000
Molecular Weight:Calculated MW:54 kDa; Observed MW:54, 25 kDa
Purification:Affinity Purification
Form:Liquid
Synonyms:PP9284; PRSS10

Applications

WB 1:1000-1:5000,IHC 1:500-1:2000

Immunogen

A synthetic peptide of human TMPRSS2

Target Background

This gene encodes a protein that belongs to the serine protease family. The encoded protein contains a type II transmembrane domain, a receptor class A domain, a scavenger receptor cysteine-rich domain and a protease domain. Serine proteases are known to be involved in many physiological and pathological processes. This gene was demonstrated to be up-regulated by androgenic hormones in prostate cancer cells and down-regulated in androgen-independent prostate cancer tissue. The protease domain of this protein is thought to be cleaved and secreted into cell media after autocleavage. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2008]

Synonyms:PP9284; PRSS10

Storage

Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.

Buffer

Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

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